selected publications
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article
- A Shortened Adeno-Associated Virus Expression Cassette for CFTR Gene Transfer to Cystic Fibrosis Airway Epithelia. Proceedings of the National Academy of Sciences of the United States of America. 102:2952-2957.
- Absence of Amiloride-Sensitive Sodium Absorption in the Airway of an Infant with Pseudohypoaldosteronism. The Journal of Pediatrics. 135:786-790.
- Activity of Abundant Antimicrobials of the Human Airway. American Journal of Respiratory Cell and Molecular Biology: An Official Journal of the American Thoacic Society, Medical Section of the American Lung Association. 20:872-880.
- Adenovirus Fiber Disrupts CAR-Mediated Intercellular Adhesion Allowing Virus Escape. Cell. 110:789-800.
- Adenovirus-Mediated Gene Transfer to Ciliated Airway Epithelia Requires Prolonged Incubation Time. Journal of Virology. 70:6994-7004.
- Adneovirus Calcium Phosphat Coprecipitates Enhance Squamous Cell Carcinoma Gene Transfer. The Laryngoscope. 111:1290-1297.
- Apical Localization of the Coxsackie-Adenovirus Receptor by Glycosyl-Phosphatidylinositol Modification is Sufficient for Adenovirus-Mediated Gene Transfer Through the Apical Surface of Human Airway Epithelia. Journal of Virology. 75:7703-7712.
- Basolateral Localization of Fiber Receptors Limits Adenovirus Infection From the Apical Surface of Airway Epithelia. The Journal of Biological Chemistry. 274:10219-10227.
- Binding of Adeno-Associated Virus Type 5 to 2, 3-Linked Sialic Acid is Required for Gene Transfer. The Journal of Biological Chemistry. 276:20610-20617.
- CFTR with a Partially Deleted R Domain Corrects the Cystic Fibrosis Chloride Transport Defect in Human Airway Epithelia in Vitro and in Mouse Nasal Muscosa in Vivo. Proceedings of the National Academy of Sciences of the United States of America. 99:3093-3099.
- Cellular and Molecular Barriers to Gene Transfer by a Cationic Lipid. The Journal of Biological Chemistry. 270:18997-19008.
- Complexes of Adenovirus with Polycationic Polymers and Cationic Lipids Increase the Efflciency of Gene Transfer in Vitro and in Vivo. The Journal of Biological Chemistry. 272:6479-6490.
- Efficient Killing of Inhaled Bacteria in DeltaF508 Mice: Role of Airway Surface Liquid Composition. American Journal of Physiology: Lung Cellular & Molecular Physiology. 21:L183-L190.
- Engineering Novel Cell Surface Receptors for Virus-Mediated Gene Transfer. The Journal of Biological Chemistry. 274:21878-21885.
- ErbB1 Functions as a Sensor of Airway Ephitelial Integrity by Regulation of Protein Phosphatase 2A Activity. Journal of Biological Chemistry. 281:1725-1730.
- Gene Transfer of CFTR to Airway Epithelia: Low Levels of Expression are Sufficient to Correct Cl-Transpost and Overexpression can Generate Basolateral CFTR. American Journal of Physiology. Lung Cellualr and Molecular Physiology. 33.
- Group D Adenoviruses Infect Primary Central Nervous System Cells More Efficiently than Those from Grouup C. Journal of Virology. 73:2537-2541.
- Inactivation of a Pseudomonas Aeruginosa Quorum-Sensing Signal by Human Airway Epithelia. Proceedings of the National Academy of Sciences of the United States of America. 101:3587-3590.
- Lysozyme Secretion by Submucosal Glands Protects the Airway from Bacterial Infection. American Journal of Respitatory Cell and Molecular Biology: An Official Journal of the American Thoracic Society, Medical Section of the American Lung Association. 32:548-553.
- Normal Sweat Chloride Values do not Exclude the Diagonsis of Cystic Fibrosis. American Journal of Respitatory and Critical Care Medicine: An Officical Journal of the American Thoracic Society, Medical Section of the American Lung Association. 152.
- Segregation of Receptor and Ligand Regulates Activation of Epithelial Growth Factor Receptor. Nature. 422:322-327.
- Targeting the Urokinase Plasminogen Activator Receptor Enhances Gene Transfer to Human Airway Epithelia. The Journal of Clinical Investigation. 105:589-597.
- The Osmolyte Xylitol Reduces the Salt Concentration of Airway Surface Liquid and May Enhance Bacterial Killing. Proceedings of the National Academy of Sciences of the United States of America. 97:11614-11620.
- Vaccinia Virus Entry, Exit, and Interaction with Differentiated Human Airway Epithelia. Journal of Virology. 81:9891-9900.